The three cytokines IL-1, IL-18, and IL-1 share related but distinct secretory routes

Tapia, VS; Daniels, MJD; Palazon-Riquelme, P; Dewhurst, M; Luheshi, NM; Rivers-Auty, J; Green, J; Redondo-Castro, E; Kaldis, P; Lopez-Castejon, G; Brough, D

Lopez-Castejon, G; Brough, D (reprint author), Univ Manchester, Lydia Becker Inst Immunol & Inflammat, Manchester M13 9PT, Lancs, England.; Brough, D (reprint author), Univ Manchester, Manchester Acad Hlth Sci Ctr, Div Neurosci & Expt Psychol, Sch Biol Sc

JOURNAL OF BIOLOGICAL CHEMISTRY, 2019; 294 (21): 8325

Abstract

Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via......

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