Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function-MedSci.cn

Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function

Sandmark, J; Tigerstrom, A; Akerud, T; Althage, M; Antonsson, T; Blaho, S; Bodin, C; Bostrom, J; Chen, YT; Dahlen, A; Eriksson, PO; Evertsson, E; Fex, T; Fjellstrom, O; Gustafsson, D; Herslof, M; Hicks, R; Jarkvist, E; Johansson, C; Kalies, I; Svalstedt, BK; Kartberg, F; Legnehed, A; Martinsson, S; Moberg, A; Ridderstrom, M; Rosengren, B; Sabirsh, A; Thelin, A; Vinblad, J; Wellner, AU; Xu, BZ; Ostlund-Lindqvist, AM; Knecht, W

Sandmark, J (corresponding author), AstraZeneca, R&D, Discovery Sci, Struct Biophys & Fragment Based Lead Generat, S-43183 Molndal, Sweden.; Knecht, W (corresponding author), AstraZeneca, BioPharmaceut R&D, Cardiovasc Renal & Metab, Biosci Cardiovasc, S-43183 Molndal, Sweden.; Knecht, W (corresponding author), Lund Univ, Dept Biol & Lund Prot Prod Platform, Solvegatan 35, S-22362 Lund, Sweden.

Abstract

Increased plasma concentrations of lipoprotein(a) (Lp(a)) are associated with an increased risk for cardiovascular disease. Lp(a) is composed of apoli......

Full Text Link

Links

内科

外科

专科科室

热点

按科室浏览

临床工具

科研工具

其他工具

科研数智化

真实世界研究解决方案

数字化学术传播解决方案

其它

Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function

科室

工具

服务