Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab)

Garces, F; Mohr, C; Zhang, L; Huang, CS; Chen, Q; King, C; Xu, C; Wang, ZL

Xu, C (corresponding author), Amgen Inc, Dept Neurosci, Amgen Res, Thousand Oaks, CA 91320 USA.; Wang, ZL (corresponding author), Amgen Inc, Dept Therapeut Discovery, Amgen Res, San Francisco, CA 94080 USA.

CELL REPORTS, 2020; 30 (6): 1714

Abstract

Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology. Aimovig (erenumab; erenumab-aooe in the United States) is the onl......

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