Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma

Tucker, ER; Tall, JR; Danielson, LS; Gowan, S; Jamin, Y; Robinson, SP; Banerji, U; Chesler, L

Chesler, L (reprint author), Inst Canc Res, Div Clin Studies, Paediat Solid Tumour Biol & Therapeut Team, Cotswold Rd, Sutton SM2 5NG, Surrey, England.; Chesler, L (reprint author), Inst Canc Res, Canc Therapeut Div, 15 Cotswold Rd, Sutton SM2 5NG, Surrey

MOLECULAR ONCOLOGY, 2017; 11 (8): 996

Abstract

Targeted inhibition of anaplastic lymphoma kinase (ALK) is a successful approach for the treatment of many ALK-aberrant malignancies; however, the pre......

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