Determination of the minimally important difference (MID) in multi-biomarker disease activity (MBDA) test scores: impact of diurnal and daily biomarker variation patterns on MBDA scores

Chernoff, D; Eastman, PS; Hwang, CC; Flake, DD; Wang, XB; Kivitz, A; Curtis, JR

Chernoff, D (reprint author), Crescendo Biosci Inc, 341 Oyster Point Blvd, San Francisco, CA 94080 USA.

CLINICAL RHEUMATOLOGY, 2019; 38 (2): 437

Abstract

The Multi-Biomarker Disease Activity (MBDA) score is a validated rheumatoid arthritis (RA) disease activity measure based on 12 serum biomarkers. Here......

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