IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3

van Geffen, EW; van Caam, APM; Schreurs, W; van de Loo, FA; van Lent, PLEM; Koenders, MI; Thudium, CS; Bay-Jensen, AC; Davidson, ENB; van der Kraan, PM

van der Kraan, PM (reprint author), Radboud Univ Nijmegen, Med Ctr, Expt Rheumatol, Geert Grootepl 28, NL-6525 GA Nijmegen, Netherlands.

OSTEOARTHRITIS AND CARTILAGE, 2019; 27 (1): 148

Abstract

Objective: A hallmark of osteoarthritis (OA) is degradation of articular cartilage proteoglycans. In isolated human OA chondrocytes, the anti-inflamma......

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