Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer

Scalesid, MK; Velez-Delgado, A; Steele, NG; Schrader, HE; Stabnick, AM; Yan, W; Soto, NMM; Nwosu, ZC; Johnson, C; Zhang, Y; Salas-Escabillas, DJ; Menjivar, RE; Maurer, HC; Crawford, HC; Bednar, F; Olive, KP; Di Magliano, MP; Allen, BL

Di Magliano, MP; Allen, BL (通讯作者),Univ Michigan, Dept Cell & Dev Biol, Ann Arbor, MI USA.;Di Magliano, MP (通讯作者),Univ Michigan, Dept Surg, Ann Arbor, MI USA.;Di Magliano, MP; Allen, BL (通讯作者),Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI USA.

PLOS GENETICS, 2022; 18 (7):

Abstract

Proper Hedgehog (HH) signaling is essential for embryonic development, while aberrant HH signaling drives pediatric and adult cancers. HH signaling is......

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