Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

Wunderlich, CM; Ackermann, PJ; Ostermann, AL; Adams-Quack, P; Vogt, MC; Tran, ML; Nikolajev, A; Waisman, A; Garbers, C; Theurich, S; Mauer, J; Hovelmeyer, N; Wunderlich, FT

Wunderlich, FT (reprint author), Univ Cologne, Max Planck Inst Metab Res Cologne, Inst Genet,CMMC,Ctr Endocrinol Diabet & Prevent M, Cologne Excellence Cluster Cellular Stress Respon, D-50931 Cologne, Germany.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

Colorectal cancer (CRC) is one of the most lethal cancers worldwide in which the vast majority of cases exhibit little genetic risk but are associated......

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