CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation

Stover, JD; Farhang, N; Berrett, KC; Gertz, J; Lawrence, B; Bowles, RD

Bowles, RD (reprint author), Univ Utah, Dept Bioengn, 20 S 2030 E,Room 108, Salt Lake City, UT 84112 USA.

MOLECULAR THERAPY, 2017; 25 (9): 2014

Abstract

Back pain is a major contributor to disability and has significant socioeconomic impacts worldwide. The degenerative intervertebral disc (IVD) has bee......

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