Translational Development Strategies for TAK-063, a Phosphodiesterase 10A Inhibitor

Macek, TA; Suzuki, K; Asin, K; Kimura, H

Kimura, H (corresponding author), 26-1,Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, Japan.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2020; 23 (8): 524

Abstract

Background: TAK-063 is an inhibitor of phosphodiesterase 10A (PDE10A), an enzyme highly expressed in medium spiny neurons of the striatum. PDE10A hydr......

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