MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with BRD4/HATs inhibitors-MedSci.cn

MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with BRD4/HATs inhibitors

Leoncini, PP; Vitullo, P; Reddel, S; Tocco, V; Paganelli, V; Stocchi, F; Mariggio, E; Massa, M; Nigita, G; Veneziano, D; Fadda, P; Scarpa, M; Pigazzi, M; Bertaina, A; Rota, R; Pagliara, D; Merli, P

Reddel, S (通讯作者)，IRCCS, Dept Paediat Haematol & Oncol, Cell & Gene Therapy, Bambino Gesu Childrens Hosp, 15 Viale San Paolo, I-00146 Rome, Italy.

Abstract

Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid Leukaemia (AML), particularly for those at high-risk for rel......

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MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with BRD4/HATs inhibitors

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