Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation

Iida, T; Hirayama, D; Minami, N; Matsuura, M; Wagatsuma, K; Kawakami, K; Nagaishi, K; Nojima, M; Ikeuchi, H; Hirota, S; Shirakawa, R; Horiuchi, H; Nakase, H

Nakase, H (corresponding author), Sapporo Med Univ, Dept Gastroenterol & Hepatol, Sch Med, Chuo Ku, Minami 1 Jo Nishi 16 Chome, Sapporo, Hokkaido 0608543, Japan.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2020; 9 (2): 277

Abstract

BACKGROUND & AIMS: Ral guanosine triphosphatase-activating protein alpha 2 (RalGAP alpha 2) is themajor catalytic subunit of the negative regulato......

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