Sunitinib-based Proteolysis Targeting Chimeras (PROTACs) reduced the protein levels of FLT-3 and c-KIT in leukemia cell lines

Zhai, JD; Li, C; Sun, BX; Wang, SA; Cui, YT; Gao, QZ; Sang, F

Gao, QZ (通讯作者)，Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin 300072, Peoples R China.;Sang, F (通讯作者)，Shandong Univ Technol, Sch Life Sci & Med, Zibo 255049, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022; 78 ():

Abstract

Proteolysis Targeting Chimeras (PROTACs) based on multi-target inhibitors have been reported several times recently. The advantages of PROTACs technol......

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