A Novel Selective 11 beta-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome-MedSci.cn

A Novel Selective 11 beta-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome

Na, YJ; Choi, KJ; Jung, WH; Park, SB; Kang, S; Ahn, JH; Kim, KY

Kim, KY (corresponding author), Korea Res Inst Chem Technol, Therapeut & Biotechnol Div, 141 Gajeong Ro, Daejeon 34114, South Korea.; Kim, KY (corresponding author), Chungnam Natl Univ, Dept New Drug Discovery & Dev, 99 Daehak Ro, Daejeon 34134, South Korea.

Abstract

Dry eye syndrome is the most common eye disease and it is caused by various reasons. As the balance of the tear film that protects the eyes is broken ......

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A Novel Selective 11 beta-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome

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