Acquired JHDM1D-BRAF Fusion Confers Resistance to FGFR Inhibition in FGFR2-Amplified Gastric Cancer

Sase, H; Nakanishi, Y; Aida, S; Horiguchi-Takei, K; Akiyama, N; Fujii, T; Sakata, K; Mio, T; Aoki, M; Ishii, N

Nakanishi, Y (reprint author), Chugai Pharmaceut Co Ltd, 200 Kajiwara, Kamakura, Kanagawa 2478530, Japan.

MOLECULAR CANCER THERAPEUTICS, 2018; 17 (10): 2217

Abstract

FGFR2 gene is frequently amplified in gastric cancer. Recently, targeting FGFR2 has drawn attention as a form of gastric cancer therapy, and FGFR-sele......

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