ApoC-III is a novel inducer of calcification in human aortic valves

Schlotter, F; Freitas, RCCD; Rogers, MA; Blaser, MC; Wu, PJ; Higashi, H; Halu, A; Iqbal, F; Andraski, AB; Rodia, CN; Kuraoka, S; Wen, JR; Creager, M; Pham, T; Hutcheson, JD; Body, SC; Kohan, AB; Sacks, FM; Aikawa, M; Singh, SA; Aikawa, E

Aikawa, E (corresponding author), Harvard Med Sch, Div Cardiovasc Med, Dept Med, Ctr Interdisciplinary Cardiovasc Sci,Brigham & Wo, Boston, MA 02115 USA.; Aikawa, E (corresponding author), Harvard Med Sch, Div Cardiovasc Med, Dept Med, Ctr Excellence Vasc Biol,Brigham & Womens Hosp, Boston, MA 02115 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ():

Abstract

Calcific aortic valve disease (CAVD) occurs when sub-populations of valve cells undergo specific differentiation pathways, promoting tissue fibrosis a......

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