PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Dosset, M; Vargas, TR; Lagrange, A; Boidot, R; Vegran, F; Roussey, A; Chalmin, F; Dondaine, L; Paul, C; Marie-Joseph, EL; Martin, F; Ryffel, B; Borg, C; Adotevi, O; Ghiringhelli, F; Apetoh, L

Apetoh, L (reprint author), INSERM, U1231, Ctr Rech, Fac Med & Pharm, 7 Bd Jeanne Arc, F-21079 Dijon, France.

ONCOIMMUNOLOGY, 2018; 7 (6):

Abstract

Background: Chemotherapy is currently evaluated in order to enhance the efficacy of immune checkpoint blockade (ICB) therapy in colorectal cancer. How......

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