Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18 alpha in colorectal cancer

Sun, SY; Hu, XT; Yu, XF; Zhang, YY; Liu, XH; Liu, YH; Wu, SH; Li, YY; Cui, SX; Qu, XJ

Qu, XJ (corresponding author), Capital Med Univ, Sch Basic Med Sci, Dept Pharmacol, Beijing, Peoples R China.; Cui, SX (corresponding author), Capital Med Univ, Sch Publ Hlth, Toxicol & Sanit Chem, Beijing, Peoples R China.

BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (11): 2351

Abstract

Background and Purpose It is well known that microsatellite instability-high (MSI-H) is associated with 5-fluorouracil (5-FU) resistance in colorectal......

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