Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair

Chaudhry, SR; Lopes, J; Levin, NK; Kalpage, H; Tainsky, MA

Tainsky, MA (corresponding author), Wayne State Univ, Sch Med, Ctr Mol Med & Genet, Detroit, MI 48202 USA.; Tainsky, MA (corresponding author), Wayne State Univ, Sch Med, Dept Oncol, Detroit, MI 48202 USA.; Tainsky, MA (corresponding author), Wayne State Univ, Sch Med, Karmanos Canc Inst, Mol Therapeut Program, Detroit, MI 48202 USA.

CELL DEATH DISCOVERY, 2021; 7 (1):

Abstract

Approximately 25% of all cases of ovarian cancer (OVCA) cases are associated with inherited risk. However, accurate risk assessment is limited by the ......

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