A new FRDA mouse model [Fxnnull:YG8s(GAA) > 800] with more than 800 GAA repeats

Kalef-Ezra, E; Edzeamey, FJ; Valle, A; Khonsari, H; Kleine, P; Oggianu, C; Al-Mahdawi, S; Pook, MA; Virmouni, SA

Virmouni, SA (通讯作者),Brunel Univ London, Dept Life Sci, Div Biosci, Ataxia Res Grp, Uxbridge, England.

FRONTIERS IN NEUROSCIENCE, 2023; 17 ():

Abstract

IntroductionFriedreich's ataxia (FRDA) is an inherited recessive neurodegenerative disorder caused by a homozygous guanine-adenine-adenine (GAA) repea......

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