Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy

Schick, R; Mekies, LN; Shemer, Y; Eisen, B; Hallas, T; Ben Jehuda, R; Ben-Ari, M; Szantai, A; Willi, L; Shulman, R; Gramlich, M; Pane, LS; My, I; Freimark, D; Murgia, M; Santamaria, G; Gherghiceanu, M; Arad, M; Moretti, A; Binah, O

Binah, O (reprint author), Technion, Dept Physiol Biophys & Syst Biol, Haifa, Israel.; Binah, O (reprint author), Rappaport Inst, Haifa, Israel.; Binah, O (reprint author), Technion, Rappaport Fac Med, Haifa, Israel.

PLOS ONE, 2018; 13 (10):

Abstract

Aims Dilated cardiomyopathy (DCM), a myocardial disorder that can result in progressive heart failure and arrhythmias, is defined by ventricular chamb......

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