Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases

Hurd, CA; Brear, P; Revell, J; Ross, S; Mott, HR; Owen, D

Mott, HR; Owen, D (corresponding author), Univ Cambridge, Dept Biochem, Cambridge, England.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ():

Abstract

Ral GTPases have been implicated as critical drivers of cell growth and metastasis in numerous Ras-driven cancers. We have previously reported stapled......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索