A single liquid chromatography-quadrupole time-of-flight mass spectrometric method for the quantification of total antibody, antibody-conjugated drug and free payload of antibody-drug conjugates

Byeon, JJ; Park, MH; Shin, SH; Lee, BI; Park, Y; Choi, J; Kim, N; Kang, Y; Shin, YG

Shin, YG (reprint author), Chungman Natl Univ, Coll Pharm, Daejeon, South Korea.

BIOMEDICAL CHROMATOGRAPHY, 2018; 32 (7):

Abstract

A single hybrid affinity-captured-LC-TOF-MS/MS method was developed and applied for the quantification of total antibody, antibody conjugated drug and......

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