Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

Smith, SH; Jayawickreme, C; Rickard, DJ; Nicodeme, E; Bui, T; Simmons, C; Coquery, CM; Neil, J; Pryor, WM; Mayhew, D; Rajpal, DK; Creech, K; Furst, S; Lee, J; Wu, DL; Rastinejad, F; Willson, TM; Viviani, F; Morris, DC; Moore, JT; Cote-Sierra, J

Smith, SH (reprint author), GlaxoSmithKline, Discovery & Preclin Dev, Dermatol TA, 20 TW Alexander Dr, Res Triangle Pk, NC 27709 USA.

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017; 137 (10): 2110

Abstract

Tapinarof (GSK2894512) is a naturally derived topical treatment with demonstrated efficacy for patients with psoriasis and atopic dermatitis, although......

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