Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity

Carew, JS; Espitia, CM; Zhao, WG; Visconte, V; Anwer, F; Kelly, KR; Nawrocki, ST

Nawrocki, ST (reprint author), Univ Arizona, Canc Ctr, Dept Med, 1515 N Campbell Ave,POB 245024, Tucson, AZ 85724 USA.

BLOOD ADVANCES, 2019; 3 (8): 1318

Abstract

Inhibition of bromodomain and extra terminal (BET) protein family members, including BRD4, decreases the expression of c-MYC and other key oncogenic f......

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