Abnormal nuclear morphology is independent of longevity in a zmpste24-deficient fish model of Hutchinson-Gilford progeria syndrome (HGPS)

Tonoyama, Y; Shinya, M; Toyoda, A; Kitano, T; Oga, A; Nishimaki, T; Katsumura, T; Oota, H; Wan, MT; Yip, BWP; Helen, MOL; Chisada, S; Deguchi, T; Au, DWT; Naruse, K; Kamei, Y; Taniguchi, Y

Taniguchi, Y (reprint author), Kyorin Univ, Sch Med, Dept Publ Hlth & Prevent Med, 6-20-2 Shinkawa, Mitaka, Tokyo 1818611, Japan.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2018; 209 (): 54

Abstract

Lamin is an intermediate protein underlying the nuclear envelope and it plays a key role in maintaining the integrity of the nucleus. A defect in the ......

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