MEK1/2 activity modulates TREM2 cell surface recruitment

Schapansky, J; Grinberg, YY; Osiecki, DM; Freeman, EA; Walker, SG; Karran, E; Gopalakrishnan, SM; Talanian, RV

Schapansky, J (corresponding author), AbbVie Inc, Cambridge Res Ctr, Cambridge, MA 02139 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ():

Abstract

Rare sequence variants in the microglial cell surface receptor TREM2 have been shown to increase the risk for Alzheimer's disease (AD). Disease-linked......

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