TAp73 Inhibits EMT and Cell Migration in Pancreatic Cancer Cells through Promoting SMAD4 Expression and SMAD4-Dependent Inhibition of ERK Activation

Ungefroren, H; Konukiewitz, B; Braun, R; Wellner, UF; Lehnert, H; Marquardt, JU

Ungefroren, H (通讯作者)，Univ Hosp Schleswig Holstein, Inst Pathol, Campus Kiel, D-24105 Kiel, Germany.;Ungefroren, H (通讯作者)，Univ Hosp Schleswig Holstein, Dept Med 1, Campus Lubeck, D-23538 Lubeck, Germany.;Ungefroren, H (通讯作者)，Univ Hosp Schleswig Holstein, Dept Surg, Campus Lubeck, D-23538 Lubeck, Germany.

CANCERS, 2023; 15 (15):

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease due to early metastatic spread, late diagnosis and the lack of efficient therapies. The aim......

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