An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug

Ozer, I; Slezak, A; Sirohi, P; Li, XH; Zakharov, N; Yao, YX; Everitt, JI; Spasojevic, I; Craig, SL; Collier, JH; Campbell, JE; D'Alessio, DA; Chilkoti, A

Chilkoti, A (通讯作者)，Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA.

BIOMATERIALS, 2023; 294 ():

Abstract

Many biologics have a short plasma half-life, and their conjugation to polyethylene glycol (PEG) is commonly used to solve this problem. However, the ......

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