HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape

Pham, LV; Jensen, SB; Fahnoe, U; Pedersen, MS; Tang, Q; Ghanem, L; Ramirez, S; Humes, D; Serre, SBN; Schonning, K; Bukh, J; Gottwein, JM

Gottwein, JM (reprint author), Copenhagen Univ Hosp, Dept Infect Dis, Copenhagen Hepatitis C Program CO HEP, Hvidovre, Denmark.; Gottwein, JM (reprint author), Univ Copenhagen, Fac Hlth & Med Sci, Dept Immunol & Microbiol, Copenhagen, Denmark.

JOURNAL OF HEPATOLOGY, 2019; 70 (3): 388

Abstract

Background & Aims: Protease inhibitors (PIs) are of central importance in the treatment of patients with chronic hepatitis C virus (HCV) infection......

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