Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

Grohmann, M; Wiede, F; Dodd, GT; Gurzov, EN; Ooi, GJ; Butt, T; Rasmiena, AA; Kaur, S; Gulati, T; Goh, PK; Treloar, AE; Archer, S; Brown, WA; Muller, M; Watt, MJ; Ohara, O; McLean, CA; Tiganis, T

Tiganis, T (reprint author), Monash Univ, Monash Biomed Discovery Inst, Clayton, Vic 3800, Australia.; Tiganis, T (reprint author), Peter MacCallum Canc Ctr, Melbourne, Vic 3000, Australia.

CELL, 2018; 175 (5): 1289

Abstract

Obesity is a major driver of cancer, especially hepatocellular carcinoma (HCC). The prevailing view is that non-alcoholic steatohepatitis (NASH) and f......

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