Identfication of Potent LXR beta-Selective Agonists without LXR alpha Activation by In Silico Approaches

Chen, MM; Yang, FF; Kang, J; Gan, HJ; Yang, XM; Lai, XM; Gao, YX

Chen, MM (reprint author), Fujian Univ Tradit Chinese Med, Coll Tradit Chinese Med, Fuzhou 350122, Fujian, Peoples R China.; Chen, MM; Yang, FF (reprint author), Fujian Normal Univ, Coll Chem & Mat Sci, Fuzhou 350007, Fujian, Peoples R China.

MOLECULES, 2018; 23 (6):

Abstract

Activating Liver X receptors (LXRs) represents a promising therapeutic option for dyslipidemia. However, activating LXR alpha may cause undesired lipo......

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