CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs

Sakuma, K; Tsubooka-Yamazoe, N; Hashimoto, K; Sakai, N; Asano, S; Watanabe-Matsumoto, S; Watanabe, T; Saito, B; Matsumoto, H; Ueno, H; Ito, R; Toyoda, T

Sakuma, K (通讯作者)，Orizuru Therapeut Inc, iPSC Derived Pancreat Islet Cell iPIC Therapy Dep, Fujisawa, Kanagawa 2518555, Japan.;Sakuma, K; Toyoda, T (通讯作者)，Takeda CiRA Joint Program iPS Cell Applicat T CiR, Fujisawa, Kanagawa 2518555, Japan.

STEM CELL RESEARCH & THERAPY, 2023; 14 (1):

Abstract

Background: Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. El......

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