Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition

Yang, L; Zhang, YY; Shan, WW; Hu, ZY; Yuan, J; Pi, JJ; Wang, YY; Fan, LL; Tang, ZQ; Li, CS; Hu, XW; Tanyi, JL; Fan, Y; Huang, QH; Montone, K; Dang, CV; Zhang, L

Zhang, L (reprint author), Univ Penn, Ctr Res Reprod & Womens Hlth, Philadelphia, PA 19104 USA.; Zhang, L (reprint author), Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA.; Zhang, L (reprint author), Univ Penn, Abramson Canc Ctr, Philadelphi

SCIENCE TRANSLATIONAL MEDICINE, 2017; 9 (400):

Abstract

Strategies to enhance response to poly(adenosine diphosphate-ribose) polymerase inhibitor (PARPi) in primary and acquired homologous recombination (HR......

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