The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice

Chu, HK; Jiang, L; Gao, B; Gautam, N; Alamoudi, JA; Lang, S; Wang, YH; Duan, Y; Alnouti, Y; Cable, EE; Schnabl, B

Schnabl, B (corresponding author), Univ Calif San Diego, Dept Med, MC0063,9500 Gilman Dr, La Jolla, CA 92093 USA.

TRANSLATIONAL RESEARCH, 2021; 227 (): 1

Abstract

Alcohol-associated liver disease is accompanied by dysregulation of bile acid metabolism and gut barrier dysfunction. Peroxisome proliferator-activate......

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