Nexinhib20 Inhibits Neutrophil Adhesion and b(2) Integrin Activation by Antagonizing Rac-1-Guanosine 5'-Triphosphate Interaction

Liu, W; Cronin, CG; Cao, ZM; Wang, CL; Ruan, JB; Pulikkot, S; Hall, A; Sun, H; Groisman, A; Chen, YF; Vella, AT; Hu, L; Liang, BT; Fan, ZC

Fan, ZC (通讯作者),UConn Hlth, Sch Med, Dept Immunol, 263 Farmington Ave, Farmington, CT 06030 USA.;Liang, BT (通讯作者),UConn Hlth, Pat & Jim Calhoun Cardiol Ctr, Sch Med, 263 Farmington Ave, Farmington, CT 06030 USA.

JOURNAL OF IMMUNOLOGY, 2022; 209 (8): 1574

Abstract

Neutrophils are critical for mediating inflammatory responses. Inhibiting neutrophil recruitment is an attractive approach for preventing inflammatory......

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