Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia

Reiter, K; Polzer, H; Krupka, C; Maiser, A; Vick, B; Rothenberg-Thurley, M; Metzeler, KH; Dorfel, D; Salih, HR; Jung, G; Nossner, E; Jeremias, I; Hiddemann, W; Leonhardt, H; Spiekermann, K; Subklewe, M; Greif, PA

Greif, PA (reprint author), Ludwig Maximilians Univ Munchen, Univ Hosp, Dep Med 3, Max Lebsche Pl 30, D-81377 Munich, Germany.

LEUKEMIA, 2018; 32 (2): 313

Abstract

The fms-related tyrosine kinase 3 (FLT3) receptor has been extensively studied over the past two decades with regard to oncogenic alterations that do ......

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