Targeting TKI-Activated NFKB2-MIF/CXCLs-CXCR2 Signaling Pathways in FLT3 Mutated Acute Myeloid Leukemia Reduced Blast Viability

Cao, H; Tadros, V; Hiramoto, B; Leeper, K; Hino, C; Xiao, J; Pham, B; Kim, D; Reeves, ME; Chen, CS; Zhong, JF; Zhang, KK; Xie, LL; Wasnik, S; Baylink, DJ; Xu, Y

Xu, Y (通讯作者)，Loma Linda Univ, Dept Med, Div Hematol & Oncol, Loma Linda, CA 92354 USA.;Xu, Y (通讯作者)，Loma Linda Univ, Ctr Canc, Loma Linda, CA 92354 USA.;Xu, Y (通讯作者)，Loma Linda Univ, Dept Med, Div Regenerat Med, Loma Linda, CA 92354 USA.

BIOMEDICINES, 2022; 10 (5):

Abstract

Disease relapse is a common cause of treatment failure in FMS-like tyrosine kinase 3 (FLT3) mutated acute myeloid leukemia (AML). In this study, to id......

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