Proteasome Inhibition Overcomes ALK-TKI Resistance in ALK-Rearranged/TP53-Mutant NSCLC via Noxa Expression

Tanimoto, A; Matsumoto, S; Takeuchi, S; Arai, S; Fukuda, K; Nishiyama, A; Yoh, K; Ikeda, T; Furuya, N; Nishino, K; Ohe, Y; Goto, K; Yano, S

Tanimoto, A (corresponding author), Kanazawa Univ, Canc Res Inst, 13-1 Takara Machi, Kanazawa, Ishikawa 9200934, Japan.

CLINICAL CANCER RESEARCH, 2021; 27 (5): 1410

Abstract

Purpose: In ALK-rearranged non-small cell lung cancer (NSCLC), impacts of concomitant genetic alterations on targeted therapies with ALK-tyrosine kina......

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