Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat

Barrett, RRG; Nash, C; Diennet, M; Cotnoir-White, D; Doyle, C; Mader, S; Thomson, AA; Gleason, JL

Gleason, JL (通讯作者),McGill Univ, Dept Chem, 801 Sherbrooke W, Montreal, PQ H3A 0B8, Canada.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022; 55 ():

Abstract

The combination of androgen receptor antagonists with histone deacetylase inhibitors (HDACi) has been shown to be more effective than antiandrogens al......

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