MDM2-PROTAC versus MDM2 Inhibitors: Beyond p53 Reactivation

Peuget, S; Selivanova, G

Selivanova, G (通讯作者),Karolinska Inst, Biomedicum C8,Solnavagen 9, S-17165 Stockholm, Sweden.

CANCER DISCOVERY, 2023; 13 (5): 1043

Abstract

In this issue of Cancer Discovery , Adams and colleagues present the discovery of a potent PROTAC, MDM2 degrader, which activates wild-type p53 leadin......

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