Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma

Carneiro, BA; Papadopoulos, KP; Strickler, JH; Lassman, AB; Waqar, SN; Chae, YK; Patel, JD; Shacham-Shmueli, E; Kelly, K; Khasraw, M; Bestvina, CM; Merrell, R; Huang, K; Atluri, H; Ansell, P; Li, R; Jin, J; Anderson, MG; Reilly, EB; Morrison-Thiele, G; Patel, K; Robinson, RR; Aristide, MRN; Gan, HK

Carneiro, BA (通讯作者)，Brown Univ, Legorreta Canc Ctr, Providence, RI 02903 USA.;Carneiro, BA (通讯作者)，Lifespan Canc Inst, Providence, RI USA.

NEURO-ONCOLOGY ADVANCES, 2023; 5 (1):

Abstract

Background. Serclutamab talirine (Ser-T, formerly ABBV-321) is an antibody-drug conjugate consisting of an antibody (AM-1-ABT-806) directed against ac......

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