Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib

Yao, JW; Man, SL; Dong, HH; Yang, L; Ma, L; Gao, WY

Man, SL (reprint author), Tianjin Univ Sci & Technol, Coll Biotechnol, Natl & Local United Engn Lab Metab Control Fermen, Key Lab Ind Microbiol,Minist Educ,Tianjin Key Lab, Tianjin 300457, Peoples R China.; Gao, WY (reprint author), Tianjin Univ, Sch Phar

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2018; 183 (): 159

Abstract

Sorafenib, as a multi-kinase inhibitor, was the first FDA-approved anti- hepatocellular carcinoma (HCC) drug. Rhizoma Paridis saponins (RPS) as natura......

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