TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG)

Werbrouck, C; Evangelista, CCS; Lobon-Iglesias, MJ; Barret, E; Le Teuff, G; Merlevede, J; Brusini, R; Kergrohen, T; Mondini, M; Bolle, S; Varlet, P; Beccaria, K; Boddaert, N; Puget, S; Grill, J; Debily, MA; Castel, D

Castel, D (reprint author), Gustave Roussy, 114 Rue Edouard Vaillant, F-94805 Villejuif, France.

CLINICAL CANCER RESEARCH, 2019; 25 (22): 6788

Abstract

Purpose: Diffuse intrinsic pontine gliomas (DIPG) are the most severe pediatric brain tumors. Although accepted as the standard therapeutic, radiother......

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