Aurora-A-mediated phosphorylation of LKB1 compromises LKB1/AMPK signaling axis to facilitate NSCLC growth and migration

Zheng, X; Chi, J; Zhi, J; Zhang, H; Yue, D; Zhao, J; Li, D; Li, Y; Gao, M; Guo, J

Gao, M; Guo, J (reprint author), Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Pathol, E CLS 628,3 Blackfan Circle, Boston, MA 02115 USA.

ONCOGENE, 2018; 37 (4): 502

Abstract

Deletion or loss-of-function mutation of LKB1, frequently occurring in non-small cell lung cancers (NSCLCs), is a predominant caution of NSCLC initiat......

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