Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice

Peuhu, E; Salomaa, SI; De Franceschi, N; Potter, CS; Sundberg, JP; Pouwels, J

Peuhu, E; Pouwels, J (reprint author), Univ Turku, Turku Ctr Biotechnol, Turku, Finland.; Pouwels, J (reprint author), Univ Helsinki, TEHO Adapt Clin Trial Design, Helsinki, Finland.

PLOS ONE, 2017; 12 (10):

Abstract

SHARPIN (Shank-Associated RH Domain-Interacting Protein) is a component of the linear ubiquitin chain assembly complex (LUBAC), which enhances TNF-ind......

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