Activity of tarloxotinib-E in cells with EGFR exon-20 insertion mutations and mechanisms of acquired resistance

Nishino, M; Suda, K; Koga, T; Ohara, S; Fujino, T; Soh, J; Tirunagaru, V; Vellanki, A; Doebele, RC; Mitsudomi, T

Suda, K (corresponding author), Kindai Univ, Div Thorac Surg, Dept Surg, Fac Med, 377-2 Ohno Higashi, Osaka 5898511, Japan.

THORACIC CANCER, ; ():

Abstract

Background Approximately 10% of non-small cell lung cancers (NSCLCs) that harbor epidermal growth factor receptor (EGFR) gene mutations have in-frame ......

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