A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression

Rigamonti, N; Veitonmaki, N; Domke, C; Barsin, S; Jetzer, S; Abdelmotaleb, O; Bessey, R; Lekishvili, T; Malvezzi, F; Gachechiladze, M; Behe, M; Levitsky, V; Trail, PA

Rigamonti, N (通讯作者)，Mol Partners AG, Wagistr 14, CH-8952 Zurich, Switzerland.

CANCER IMMUNOLOGY RESEARCH, 2022; 10 (5): 626

Abstract

The CD40 receptor is an attractive target for cancer immunotherapy. Although a modest pharmacodynamic effect is seen in patients following administrat......

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