Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss

Yoshida, A; Phillips-Mason, P; Tarallo, V; Avril, S; Koivisto, C; Leone, G; Diehl, JA

Yoshida, A (通讯作者),Univ Hosp Cleveland, Dept Dermatol, Med Ctr, Cleveland, OH 44106 USA.;Yoshida, A (通讯作者),Case Western Reserve Univ, Cleveland, OH 44106 USA.;Yoshida, A; Diehl, JA (通讯作者),Case Western Reserve Univ, Dept Biochem, Cleveland, OH 44106 USA.;Yoshida, A; Diehl, JA (通讯作者),Case Western Reserve Univ, Case Comprehens Canc Ctr, Cleveland, OH 44106 USA.

ONCOGENE, 2022; 41 (15): 2187

Abstract

Cyclin D1 is a regulatory subunit of -Cyclin Dependent Kinases 4 and 6 (CDK4/6) and regulates progression from G1 to S phase of the cell cycle. Dysreg......

Full Text Link