IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines

Levy, T; Marchand, L; Stroobant, V; Pilotte, L; Van den Eynde, B; Rodriguez, F; Delfourne, E

Delfourne, E (corresponding author), Univ Paul Sabatier, UMR CNRS 5068, Lab Synth & Physicochim Mol Interet Biol, 118 Route Narbonne, F-31062 Toulouse 9, France.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021; 40 ():

Abstract

Indoleamine 2,3-dioxygenase (IDO1) and tryptophane 2,3-dioxygenase (TDO) are two heme-containing enzymes which catalyze the conversion of tryptophan t......

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